In the last two decades, many professionals have manifested the necessity to make of the prevention a scientific discipline, in which one works on the basis of the objective evidence, without leaving place to practical intuitive and/or simply based on the good will. Like result, today we have a solid empirical base about the school strategies that obtain results in the consumption and those that not, and even those that are against preventive. Nevertheless, when reviewing the investigations developed in this area, a wide variability in the sizes of the effects of the interventions is verified, wich indicates the necessity to us to verify what characteristic of the preventive programs are those responsible for this variability. The aim of the study is to describe the associated characteristics of the most effective interventions, developed in the school environment. For it, the results of four revisions of revisions that have summarized in a systematized way the evidence available by diverse studies of revisions and meta-analyses are synthesized it.